Phase I Objective:

The objective of Phase I of this study is to evaluate the risks on equine of the supplement hereafter referred to as Sefacon™. The scope of the evaluation was limited to equine that are in reasonably good health with no obvious deficits.  

5 control equine were selected for this phase. The following information details the results of Phase I of the analysis.  

Dosage:

For the purposes of this Phase of the evaluation we have used the standard dose of 20 mL twice daily for four days and 20 mL once daily for the following six days, on four of the control equine.  The fifth control equine will be given 100 ml of Sefacon™ twice a day to establish the positive or negative effect.

Evaluation Results:

Control horses 1 - 4 (various breeds and genders, aged 2 – 21 years). Control horses had no clinical signs of any neurological disorders and all appeared to be in good health and condition.  They were given the standard dosage of Sefacon™.  They manifested no signs of any discomfort, loss of appetite, weight loss or any other negative effects from the standard serving.

Toxicity:

Control horse 5 (20-year-old Standardbred gelding).  This horse had no clinical signs of any neurological disorders.  He does, however, have a thyroid condition for which he receives continual treatment.  This treatment was suspended for 5 days pre and post application of Sefacon™.  He was given 100 mL twice during a 24-hour period and did not manifest any signs of discomfort, loss of appetite, weight loss or loose bowel.  He was kept under close observation for 48 hours after ingestion.

Phase I Conclusion:

Phase I of the study concluded with no harmful effects of Sefacon to any of the 4 control horses selected and no effects noted on the fifth control horse given 5 times the standard dosage.

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For information on obtaining Sefacon™ contact 
Endocrine Technologies, Inc or Indiana Horse Rescue

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